Higher-level gait disorders: an open frontier

Mov Disord. 2013 Sep 15;28(11):1560-5. doi: 10.1002/mds.25673.

Abstract

The term higher-level gait disorders (HLGD) defines a category of balance and gait disorders that are not explained by deficits in strength, tone, sensation, or coordination. HLGD are characterized by various combinations of disequilibrium and impaired locomotion. A plethora of new imaging techniques are beginning to determine the neural circuits that are the basis of these disorders. Although a variety of neurodegenerative and other pathologies can produce HLGD, the most common cause appears to be microvascular disease that causes white-matter lesions and thereby disrupts balance/locomotor circuits.

Keywords: balance; falls; gait; gait disorders; locomotor circuits.

Publication types

  • Review

MeSH terms

  • Gait Disorders, Neurologic / classification*
  • Gait Disorders, Neurologic / diagnosis
  • Gait Disorders, Neurologic / physiopathology*
  • Humans
  • Locomotion
  • Neuroimaging
  • Psychomotor Performance