Usefulness of India ink artifact in steady-state free precession pulse sequences for detection and quantification of intramyocardial fat

J Magn Reson Imaging. 2014 Jul;40(1):126-32. doi: 10.1002/jmri.24335. Epub 2013 Oct 11.

Abstract

Purpose: In steady state free precession (SSFP) images acquired with a repetition time/echo time (TR/TE) ≈ 2, fat is surrounded by a black boundary, called "India Ink" artifact. Indian Ink artifact may improve detection of intramyocardial fat. Aims of this study were: (i) to assess the accuracy of SSFP technique for the detection of fat metaplasia in remote myocardial infarction (RMI); (ii) to evaluate the inter- and intraobserver reproducibility for the quantification of intramyocardial fat using SSFP and fast spin echo/short TI inversion recovery (FSE/STIR) techniques.

Materials and methods: A total of 200 patients (age 64 ± 10 years) with RMI (>1000 days) underwent MRI using a 1.5 Tesla (T) scanner. SSFP images (with a TR/TE ≈2), FSE and STIR images were acquired in short and long axis views. Fat was detected in FSE/STIR and SSFP images and its extent manually measured . The inter- and intraobserver agreement for the quantification of fat metaplasia using both the SSFP image and the FSE images was evaluated.

Results: Left ventricle intramyocardial fat was detected in SSFP images of 95 patients (47.5%) and in FSE/STIR images of 84 patients (42%). A very good agreement was found using the SSFP technique between investigators.

Conclusion: SSFP sequence with TR/TE=2 is a valuable technique for identifying and quantifying the presence of fat tissue within the left ventricle myocardium in RMI.

Keywords: FSE; India Ink artifact; Myocardial infarction; SSFP; STIR; left ventricular fat metaplasia.

Publication types

  • Evaluation Study

MeSH terms

  • Adipose Tissue / pathology*
  • Artifacts*
  • Carbon*
  • Female
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Myocardial Infarction / pathology*
  • Observer Variation
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted

Substances

  • chinese ink
  • Carbon