Discovery of chemoselective and biocompatible reactions using a high-throughput immunoassay screening

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12056-60. doi: 10.1002/anie.201305645. Epub 2013 Oct 7.
No abstract available

Keywords: click chemistry; copper; high-throughput screening; immunoassay; reaction discovery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry
  • Animals
  • Azides / chemistry
  • Biocompatible Materials / analysis*
  • Catalysis
  • Cattle
  • Copper / chemistry
  • Cycloaddition Reaction
  • High-Throughput Screening Assays*
  • Immunoassay*
  • Phosphatidylcholines / chemistry
  • Serum Albumin, Bovine / chemistry
  • Sydnones / chemistry

Substances

  • 1-myristoyl-2-(12-((5-dimethylamino-1-naphthalenesulfonyl)amino)dodecanoyl)-sn-glycero-3-phosphocholine
  • Alkynes
  • Azides
  • Biocompatible Materials
  • Phosphatidylcholines
  • Sydnones
  • Serum Albumin, Bovine
  • Copper