Generation of HNO and HSNO from nitrite by heme-iron-catalyzed metabolism with H₂S

Angew Chem Int Ed Engl. 2013 Nov 11;52(46):12061-4. doi: 10.1002/anie.201305669. Epub 2013 Sep 25.
No abstract available

Keywords: hydrogen sulfide; nitrite; porphyrinoids; reduction; thionitrous acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electron Spin Resonance Spectroscopy
  • Heme / chemistry*
  • Human Umbilical Vein Endothelial Cells
  • Humans
  • Hydrogen Sulfide / chemistry*
  • Hydrogen Sulfide / pharmacology
  • Iron / chemistry*
  • Mitochondria / drug effects
  • Mitochondria / metabolism
  • Nitric Oxide / metabolism
  • Nitrites / chemistry*
  • Nitrogen Oxides / chemistry*
  • Nitrous Acid / chemistry*
  • Porphyrins / chemistry
  • Sulfur Compounds / chemistry*

Substances

  • Nitrites
  • Nitrogen Oxides
  • Porphyrins
  • Sulfur Compounds
  • Nitric Oxide
  • Heme
  • Iron
  • nitroxyl
  • Nitrous Acid
  • Hydrogen Sulfide