The synthesis, structure elucidation and the complete (1)H and (13)C signal assignment of a series of dioxolane derivatives of 20-hydroxyecdysone, synthesized as novel modulators of multidrug resistance, are presented. The structures and NMR signal assignment were established by comprehensive one-dimensional and two-dimensional NMR spectroscopy supported by mass spectrometry.
Keywords: 13C NMR; 1H NMR; 20-hydroxyecdysone dioxolanes; P-glycoprotein; antitumor agents; stereochemistry.
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