Hyperprolactinaemia, amenorrhoea and galactorrhoea due to a pituitary thyrotroph adenoma

Clin Endocrinol (Oxf). 1985 Jul;23(1):35-42. doi: 10.1111/j.1365-2265.1985.tb00180.x.

Abstract

A case of hyperprolactinaemia/amenorrhoea-galactorrhoea syndrome is described. A prolactinoma was diagnosed, but histology of the excised tumour revealed it to be a thyrotoph adenoma. alpha-subunit and beta-TSH levels were lowered after the operation. The significance of this tumour is discussed.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / complications*
  • Adenoma / metabolism
  • Adenoma / pathology
  • Adult
  • Amenorrhea / etiology*
  • Female
  • Galactorrhea / etiology*
  • Glycoprotein Hormones, alpha Subunit
  • Humans
  • Lactation Disorders / etiology*
  • Peptide Fragments / blood
  • Pituitary Hormones, Anterior / blood
  • Pituitary Neoplasms / complications*
  • Pituitary Neoplasms / metabolism
  • Pituitary Neoplasms / pathology
  • Pregnancy
  • Prolactin / blood*
  • Thyrotropin / blood
  • Thyrotropin / metabolism

Substances

  • Glycoprotein Hormones, alpha Subunit
  • Peptide Fragments
  • Pituitary Hormones, Anterior
  • Prolactin
  • Thyrotropin