Retrospective review of pharyngeal gonorrhea treatment failures in Alberta, Canada

Sex Transm Dis. 2013 Nov;40(11):877-9. doi: 10.1097/OLQ.0000000000000033.

Abstract

Our review of Neisseria gonorrhoeae pharyngeal treatment failures from sexually transmitted infection clinics in Alberta suggests that treatment failures with oral cefixime monotherapy were not related to elevated cefixime minimum inhibitory concentrations. Dual therapy with oral cefixime and azithromycin may be a suitable alternate for the treatment of pharyngeal gonorrhea.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alberta / epidemiology
  • Anti-Bacterial Agents / therapeutic use*
  • Azithromycin / therapeutic use*
  • Cefixime / therapeutic use*
  • Drug Therapy, Combination
  • Female
  • Gonorrhea / drug therapy*
  • Gonorrhea / epidemiology
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Neisseria gonorrhoeae / drug effects*
  • Neisseria gonorrhoeae / isolation & purification
  • Pharyngeal Diseases / drug therapy*
  • Pharyngeal Diseases / epidemiology
  • Pharyngeal Diseases / microbiology
  • Pharynx / microbiology*
  • Pharynx / pathology
  • Retrospective Studies
  • Sexual Behavior / statistics & numerical data
  • Treatment Failure

Substances

  • Anti-Bacterial Agents
  • Azithromycin
  • Cefixime