Phylogenetic analysis and molecular characteristics of 17 porcine reproductive and respiratory syndrome virus isolates in Southern China from 2010 to 2011

Microb Pathog. 2013 Dec:65:67-72. doi: 10.1016/j.micpath.2013.09.005. Epub 2013 Oct 7.

Abstract

We analyzed the complete genomic sequences of 17 porcine reproductive and respiratory syndrome virus (PRRSV) isolates from Southern China obtained between 2010 and 2011 and found that four of seven isolates from 2011 were closely related to the JXA1-R strain (vaccine virus of JXA1). This close relationship between field isolates and China domestic vaccine viruses has not been reported to date. The occurrence of vaccine-like viruses potentially creates a threat for the pig breeding industry and brings difficulties for control of this disease.

Keywords: Complete genome; GP5; Nsp2; PRRSV.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • China / epidemiology
  • Genetic Variation
  • Genome, Viral
  • Genotype
  • Molecular Sequence Data
  • Phylogeny
  • Porcine Reproductive and Respiratory Syndrome / epidemiology
  • Porcine Reproductive and Respiratory Syndrome / immunology
  • Porcine Reproductive and Respiratory Syndrome / virology*
  • Porcine respiratory and reproductive syndrome virus / classification*
  • Porcine respiratory and reproductive syndrome virus / genetics
  • Porcine respiratory and reproductive syndrome virus / isolation & purification
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Swine
  • Vaccines / genetics*

Substances

  • Vaccines