Estimating reliable paediatric reference intervals in clinical chemistry and haematology

Acta Paediatr. 2014 Jan;103(1):10-5. doi: 10.1111/apa.12438. Epub 2013 Oct 30.

Abstract

Very few high-quality studies on paediatric reference intervals for general clinical chemistry and haematology analytes have been performed. Three recent prospective community-based projects utilising blood samples from healthy children in Sweden, Denmark and Canada have substantially improved the situation.

Conclusion: The present review summarises current reference interval studies for common clinical chemistry and haematology analyses.

Keywords: Children; Clinical chemistry; Haematology; Paediatric; Reference interval.

Publication types

  • Review

MeSH terms

  • Blood Chemical Analysis / standards*
  • Child
  • Hematology / standards
  • Humans
  • Pediatrics / standards
  • Prospective Studies
  • Reference Values
  • Statistics as Topic