Visual evoked potential characterization of rabbit animal model for retinal prosthesis research

Annu Int Conf IEEE Eng Med Biol Soc. 2013:2013:3539-42. doi: 10.1109/EMBC.2013.6610306.

Abstract

Visual evoked potentials (VEP) are used to confirm the function of prosthetic devices designed to stimulate retinas with damaged photoreceptors in vivo. In this work, we focus on methods and experimental consideration for recording visual evoked potential in rabbit models and assesses the use for retinal prosthesis research. We compare both invasive and noninvasive methods for recording VEPs, the response of the rabbit retina to various light wavelengths and intensities, focal vs. full field stimulation, and the effect of light bleaching on the retinal response.

MeSH terms

  • Animals
  • Disease Models, Animal
  • Evoked Potentials, Visual*
  • Humans
  • Neural Prostheses
  • Photic Stimulation
  • Rabbits
  • Retina / physiology
  • Visual Prosthesis