Outcomes of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding

World J Gastroenterol. 2013 Sep 28;19(36):6035-43. doi: 10.3748/wjg.v19.i36.6035.

Abstract

Aim: To evaluate weight loss and surgical outcomes of Roux-en-Y gastric bypass (RYGB) and laparoscopic adjustable gastric band (LAGB).

Methods: Data relating to changes in body mass index (BMI) and procedural complications after RYGB (1995-2009; n = 609; 116M: 493F; 42.4 ± 0.4 years) or LAGB (2004-2009; n = 686; 131M: 555F; 37.2 ± 0.4 years) were extracted from prospective databases.

Results: Pre-operative BMI was higher in RYGB than LAGB patients (46.8 ± 7.1 kg/m² vs 40.4 ± 4.2 kg/m², P < 001); more patients with BMI < 35 kg/m² underwent LAGB than RYGB (17.1% vs 4.1%, P < 0.0001). BMI decrease was greater after RYGB. There were direct relationships between weight loss and pre-operative BMI (P < 0.001). Although there was no difference in weight loss between genders during the first 3-year post-surgery, male LAGB patients had greater BMI reduction than females (-8.2 ± 4.3 kg/m² vs -3.9 ± 1.9 kg/m², P = 0.02). Peri-operative complications occurred more frequently following RYGB than LAGB (8.0% vs 0.5%, P < 0.001); majority related to wound infection. LAGB had more long-term complications requiring corrective procedures than RYGB (8.9% vs 2.1%, P < 0.001). Conversion to RYGB resulted in greater BMI reduction (-9.5 ± 3.8 kg/m²) compared to removal and replacement of the band (-6.0 ± 3.0 kg/m²). Twelve months post-surgery, fasting glucose, total cholesterol and low density lipoprotein levels were significantly lower with the magnitude of reduction greater in RYGB patients.

Conclusion: RYGB produces substantially greater weight loss than LAGB. Whilst peri-operative complications are greater after RYGB, long-term complication rate is higher following LAGB.

Keywords: Bariatric surgery; Co-morbidity; Complications; Gastric banding; Gastric bypass; Outcomes; Weight loss.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Biomarkers / blood
  • Blood Glucose / metabolism
  • Body Mass Index
  • Chi-Square Distribution
  • Cholesterol / blood
  • Comorbidity
  • Female
  • Gastric Bypass* / adverse effects
  • Gastrointestinal Diseases / etiology
  • Gastrointestinal Diseases / surgery
  • Humans
  • Kaplan-Meier Estimate
  • Laparoscopy* / adverse effects
  • Lipoproteins, LDL / blood
  • Male
  • Obesity / blood
  • Obesity / diagnosis
  • Obesity / surgery*
  • Reoperation
  • Risk Factors
  • Sex Factors
  • Surgical Wound Infection / etiology
  • Surgical Wound Infection / surgery
  • Time Factors
  • Treatment Outcome
  • Weight Loss*

Substances

  • Biomarkers
  • Blood Glucose
  • Lipoproteins, LDL
  • Cholesterol