[Logistic regression analysis of contrast-enhanced ultrasound and ultrasonic elastography in differential diagnosis of thyroid nodules]

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Jun;48(6):495-8.
[Article in Chinese]

Abstract

Objective: To evaluate the contrast-enhanced ultrasound(CEUS) and ultrasonic elastography (UE) in diagnosis of thyroid nodules by a binary Logistic regression model.

Methods: A total 149 cases with thyroid nodules were examed by CEUS and UE and were confirmed by surgical pathology. A Logistic model was obtained on the basis of ultrasonographic features. Receiver operator characteris(ROC) curve was constructed to assess the performance of the Logistic model.

Results: Four ultrasonographic features including calcification, enhancement degree, biggest perfusion strength and elastic score were finally entered into the Logistic model. The percentage of correct prediction was 91.90%.

Conclusion: Both CEUS and UE have high value in differential diagnosis of thyroid nodules and the Logistic regression model has high diagnostic rate.

MeSH terms

  • Calcinosis
  • Contrast Media
  • Diagnosis, Differential
  • Elasticity Imaging Techniques*
  • Humans
  • Logistic Models
  • ROC Curve
  • Thyroid Nodule / diagnosis
  • Thyroid Nodule / diagnostic imaging*
  • Ultrasonics

Substances

  • Contrast Media