The association between galectin-3 and occurrence of reinfarction early after first myocardial infarction treated invasively

Biomarkers. 2013 Dec;18(8):655-9. doi: 10.3109/1354750X.2013.840801. Epub 2013 Oct 8.

Abstract

Context: Galectin-3, as a biomarker of inflammation and fibrosis, has been reported to be associated with coronary artery disease.

Objective: The study aimed to assess the relationship between galectin-3 levels and the occurrence of reinfarction early after myocardial infarction (MI).

Methods: The study included 145 consecutive patients with first MI treated invasively. Serum galectin-3 was measured using VIDAS (bioMérieux, Marcy-l'Etoile, France).

Results: The independent predictors of reinfarction in our group were as follows: female gender, elevated hs-C-reactive protein and galectin-3 levels (measured both at discharge).

Conclusions: Galectin-3 might be an additional useful biomarker in prediction for reinfarction early after first MI.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Biomarkers / metabolism*
  • Blood Proteins
  • Female
  • Galectin 3 / metabolism*
  • Galectins
  • Humans
  • Male
  • Middle Aged
  • Myocardial Infarction / metabolism
  • Myocardial Infarction / pathology*
  • Myocardial Infarction / surgery
  • Recurrence

Substances

  • Biomarkers
  • Blood Proteins
  • Galectin 3
  • Galectins
  • LGALS3 protein, human