Resistant gram-negative infections

Henry Fraimow; Raquel Nahra

doi:10.1016/j.ccc.2013.06.010

Resistant gram-negative infections

Crit Care Clin. 2013 Oct;29(4):895-921. doi: 10.1016/j.ccc.2013.06.010. Epub 2013 Aug 13.

Authors

Henry Fraimow¹, Raquel Nahra

Affiliation

¹ Department of Medicine, Cooper Medical School of Rowan University, 401 Haddon Avenue, Room 278, Camden, NJ 08103, USA. Electronic address: Fraimow-henry@cooperhealth.edu.

PMID: 24094384
DOI: 10.1016/j.ccc.2013.06.010

Abstract

This article reviews the global crisis of resistant gram-negative bacilli in the intensive care unit. The authors discuss drugs used for treating these infections and the different strategies used to maximize the effect of antimicrobials.

Keywords: Acinetobacter species; Antibiotic resistance; Enterobacteriaceae; Gram-negative bacilli; Pseudomonas aeruginosa; Septic shock.

Publication types

Review

MeSH terms

Anti-Bacterial Agents / pharmacology
Anti-Bacterial Agents / therapeutic use*
Cross Infection / drug therapy*
Drug Resistance, Multiple, Bacterial*
Drug Therapy, Combination
Gram-Negative Bacteria / classification
Gram-Negative Bacteria / drug effects*
Gram-Negative Bacterial Infections / drug therapy*
Gram-Negative Bacterial Infections / epidemiology
Humans
Intensive Care Units

Substances

Anti-Bacterial Agents