Risk factors for the progression of mild cognitive impairment to dementia

Clin Geriatr Med. 2013 Nov;29(4):873-93. doi: 10.1016/j.cger.2013.07.009.

Abstract

The increasing prevalence of cognitive impairment among the older adult population warrants attention to the identification of practices that may minimize the progression of early forms of cognitive impairment, including the transitional stage of mild cognitive impairment (MCI), to permanent stages of dementia. This article identifies both markers of disease progress and risk factors linked to the progression of MCI to dementia. Potentially modifiable risk factors may offer researchers a point of intervention to modify the effect of the risk factor and to minimize the future burden of dementia.

Keywords: Biomarkers; Dementia; Genetics; Mild cognitive impairment; Risk factors.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aged
  • Cognitive Dysfunction / complications*
  • Cognitive Dysfunction / psychology*
  • Cognitive Dysfunction / therapy
  • Dementia / diagnosis
  • Dementia / etiology*
  • Dementia / prevention & control
  • Disease Progression
  • Humans
  • Risk Factors