A recent survey on colon cancer detection techniques

IEEE/ACM Trans Comput Biol Bioinform. 2013 May-Jun;10(3):545-63. doi: 10.1109/TCBB.2013.84.

Abstract

Colon cancer causes deaths of about half a million people every year. Common method of its detection is histopathological tissue analysis, which, though leads to vital diagnosis, is significantly correlated to the tiredness, experience, and workload of the pathologist. Researchers have been working since decades to get rid of manual inspection, and to develop trustworthy systems for detecting colon cancer. Several techniques, based on spectral/spatial analysis of colon biopsy images, and serum and gene analysis of colon samples, have been proposed in this regard. Due to rapid evolution of colon cancer detection techniques, a latest review of recent research in this field is highly desirable. The aim of this paper is to discuss various colon cancer detection techniques. In this survey, we categorize the techniques on the basis of the adopted methodology and underlying data set, and provide detailed description of techniques in each category. Additionally, this study provides an extensive comparison of various colon cancer detection categories, and of multiple techniques within each category. Further, most of the techniques have been evaluated on similar data set to provide a fair performance comparison. Analysis reveals that neither of the techniques is perfect; however, research community is progressively inching toward the finest possible solution.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biopsy
  • Colonic Neoplasms / diagnosis*
  • Gene Expression Profiling
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Optical Imaging