Editorial: CD73 deficiency and immune dysregulation in HIV infection: cause or effect?

J Leukoc Biol. 2013 Oct;94(4):545-7. doi: 10.1189/jlb.0513245.

Abstract

Discussion of the challenges discerning the clinical significance of changes in CD73 expression, in human lymphocyte subsets.

Keywords: AIDS; CD39; adenosine; adenosine 5′-monophosphate; adenosine receptors; immunodeficiency; regulatory T cells.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • 5'-Nucleotidase / metabolism*
  • Animals
  • CD8-Positive T-Lymphocytes / immunology*
  • CD8-Positive T-Lymphocytes / pathology*
  • HIV Infections / immunology*
  • HIV Infections / virology*
  • Humans
  • Lymphocyte Activation / immunology*

Substances

  • 5'-Nucleotidase