Virological, serological, and antiviral studies in an imported human case of avian influenza A(H7N9) virus in Taiwan

Abstract

We describe the clinical course and virological characteristics of the first H7N9 influenza case in a Taiwanese patient; this patient had detectable viruses in the airway for 2 weeks, during which time an oseltamivir resistance-associated R292K mutation rapidly emerged. Anti-H7N9 antibody was detected 21 days after onset of symptoms, when H7N9 viral load declined significantly.

Keywords: H7N9; oseltamivir; resistance.