Fatal outcome of rhino-orbital-cerebral mucormycosis due to bilateral internal carotid occlusion in a child after hematopoietic stem cell transplantation

Pediatr Infect Dis J. 2013 Oct;32(10):1149-50. doi: 10.1097/INF.0b013e31829e69e7.

Abstract

Rhino-orbito-cerebral mucormycosis is a rare fulminant opportunistic fungal infection that particularly occurs in immunocompromised patients. We present a case of fatal invasive rhino-orbito-cerebral mucormycosis complicated by bilateral thrombotic occlusion of the internal carotid artery with consequent cerebral infarction in a 5-year-old boy after hematopoietic stem cell transplantation for acute pre-B-cell lymphoblastic leukemia.

Publication types

  • Case Reports

MeSH terms

  • Brain Diseases / microbiology
  • Brain Diseases / pathology*
  • Carotid Artery Thrombosis / pathology*
  • Child, Preschool
  • Fatal Outcome
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Male
  • Mucormycosis / pathology*
  • Nose Diseases / microbiology
  • Nose Diseases / pathology
  • Opportunistic Infections / microbiology
  • Opportunistic Infections / pathology*
  • Orbital Diseases / microbiology
  • Orbital Diseases / pathology
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / surgery