Abstract
With the employment of a threonine-incorporating multifunctional catalyst 9, Michael addition of 3-sulfenyloxindoles to nitroolefins proceeded stereoselectively, leading to the formation of oxindoles with a 3-sulfenyl-substituted quaternary center in excellent yields, and with high diastereoselectivities and excellent enantioselectivities.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Catalysis
-
Indoles / chemical synthesis*
-
Indoles / chemistry
-
Molecular Structure
-
Nitro Compounds / chemical synthesis*
-
Nitro Compounds / chemistry
-
Oxindoles
-
Stereoisomerism
-
Sulfhydryl Compounds / chemistry*
Substances
-
Indoles
-
Nitro Compounds
-
Oxindoles
-
Sulfhydryl Compounds
-
2-oxindole