Light-controlled ion channels formed by amphiphilic small molecules regulate ion conduction via cis-trans photoisomerization

Chem Commun (Camb). 2013 Nov 11;49(87):10311-3. doi: 10.1039/c3cc45618h.

Abstract

Light-regulated ion channel-transport across lipid bilayers was realized using structurally simple azobenzene-based amphiphilic small molecules. UV or visible irradiation triggers molecular photoisomerization, which induces structural and membrane affinity changes in self-assembled channels, thus resulting in light-regulated ion transmembrane transport.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Azo Compounds / chemistry*
  • Electric Conductivity
  • Electron Transport
  • Ion Channels / chemistry*
  • Light*
  • Lipid Bilayers / chemistry
  • Models, Molecular
  • Molecular Structure
  • Photochemical Processes
  • Stereoisomerism
  • Surface-Active Agents / chemistry*
  • Ultraviolet Rays*

Substances

  • Azo Compounds
  • Ion Channels
  • Lipid Bilayers
  • Surface-Active Agents
  • azobenzene