Iron absorption from NaFeEDTA-fortified oat beverages with or without added vitamin C

Int J Food Sci Nutr. 2014 Feb;65(1):124-8. doi: 10.3109/09637486.2013.836739. Epub 2013 Sep 24.

Abstract

Background: Food fortification is the best long-term approach for reducing the incidence of iron deficiency.

Objective: To determine iron absorption from NaFeEDTA-fortified oat beverages without and with vitamin C.

Materials and methods: Iron absorption in 19 apparently healthy 6-year-old children was studied. Two oat beverages fortified with iron (labeled with stable isotopes of NaFeEDTA), zinc, and vitamin A, without and with vitamin C was consumed in two consecutive days in random order. Blood samples were taken 14 days later for stable isotope measurements.

Results: The mean fractional iron absorption from the fortified oat beverage without vitamin C (5.65 ± 0.54%) was significantly lower than that from the beverage with vitamin C (7.14 ± 0.90%; p < 0.05).

Conclusion: Fortified oat beverages may offer a convenient and effective mechanism to improve the iron status of children. The addition of vitamin C improved iron absorption by an additional 1.5%.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ascorbic Acid / administration & dosage
  • Ascorbic Acid / metabolism*
  • Avena / chemistry*
  • Beverages* / analysis
  • Breakfast
  • Child
  • Cross-Over Studies
  • Double-Blind Method
  • Edetic Acid / chemistry
  • Female
  • Ferric Compounds / chemistry
  • Food, Fortified* / analysis
  • Food, Preserved / analysis
  • Humans
  • Inositol Phosphates / adverse effects
  • Inositol Phosphates / analysis
  • Intestinal Absorption*
  • Iron Chelating Agents / chemistry
  • Iron Isotopes
  • Iron, Dietary / administration & dosage
  • Iron, Dietary / blood
  • Iron, Dietary / metabolism*
  • Male
  • Philippines
  • Phytic Acid / adverse effects
  • Phytic Acid / analysis
  • Seeds / chemistry*
  • Zinc / administration & dosage
  • Zinc / metabolism

Substances

  • Ferric Compounds
  • Inositol Phosphates
  • Iron Chelating Agents
  • Iron Isotopes
  • Iron, Dietary
  • Phytic Acid
  • Edetic Acid
  • Zinc
  • Fe(III)-EDTA
  • Ascorbic Acid