Risk factors for intraoperative hemorrhage at evacuation of a cesarean scar pregnancy following uterine artery embolization

Int J Gynaecol Obstet. 2013 Dec;123(3):240-3. doi: 10.1016/j.ijgo.2013.06.029. Epub 2013 Sep 3.

Abstract

Objective: To determine risk factors associated with massive uterine bleeding during dilation and suction curettage (D&C) after uterine artery embolization (UAE) for the treatment of cesarean scar pregnancy (CSP).

Methods: Data from 128 CSP patients treated with D&C after UAE were analyzed to assess risk factors associated with massive uterine bleeding (blood loss 500mL or more) during D&C after UAE.

Results: In total, 15 CSP patients had massive bleeding during D&C after UAE. Univariate analysis showed that a greater gestational age (GA), a larger CSP mass size, a thinner myometrium at the implantation site, a GA of 8weeks or more, a CSP mass diameter of 6cm or more, and evidence of fetal heartbeat were risk factors for massive bleeding (P<0.05). In a binary logistic regression analysis, GA of 8weeks or more and CSP mass diameter of 6cm or more remained as the only significant risk factors for massive bleeding (OR 11.49 [95% CI 1.08-122.13] and OR 96.59 [95% CI 6.20-150.57], respectively; P<0.05).

Conclusion: For CSP masses with a GA of 8weeks or more and a diameter of 6cm or more, the outcome of surgical evacuation after UAE tends to be unsatisfactory.

Keywords: Cesarean scar pregnancy; Curettage; Methotrexate; Uterine artery embolization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Loss, Surgical
  • Cesarean Section / adverse effects
  • Cicatrix / etiology
  • Cicatrix / pathology
  • Combined Modality Therapy
  • Dilatation and Curettage / methods*
  • Female
  • Gestational Age
  • Humans
  • Logistic Models
  • Middle Aged
  • Myometrium / pathology
  • Pregnancy
  • Pregnancy, Ectopic / therapy*
  • Risk Factors
  • Uterine Artery Embolization / methods*
  • Uterine Hemorrhage / epidemiology*
  • Uterine Hemorrhage / etiology
  • Young Adult