Continuous flow synthesis

Jun-ichi Yoshida; Aiichiro Nagaki; Daisuke Yamada

doi:10.1016/j.ddtec.2012.10.013

Continuous flow synthesis

Drug Discov Today Technol. 2013 Spring;10(1):e53-9. doi: 10.1016/j.ddtec.2012.10.013.

Authors

Jun-ichi Yoshida, Aiichiro Nagaki, Daisuke Yamada

PMID: 24050230
DOI: 10.1016/j.ddtec.2012.10.013

Abstract

This article provides a brief outline of continuous flow synthesis including the advantages of the flow method, serial combinatorial synthesis in flow, space integration of reactions, and reactions that cannot be done in batch to show that continuous flow synthesis will be a powerful and indispensable technology for pharmaceutical research and production.

Publication types

Review

MeSH terms

Chemistry, Organic / instrumentation
Chemistry, Organic / methods*
Chemistry, Pharmaceutical / instrumentation
Chemistry, Pharmaceutical / methods*
Combinatorial Chemistry Techniques*
Drug Discovery