Labelling studies on the biosynthesis of terpenes in Fusarium fujikuroi

Chem Commun (Camb). 2014 May 25;50(40):5224-6. doi: 10.1039/c3cc45982a. Epub 2013 Sep 19.

Abstract

Synthetic [2-(13)C]mevalonolactone was fed to the gibberellin producer Fusarium fujikuroi and its incorporation into four known terpenoids was investigated by (13)C NMR analysis of crude culture extracts. The experiments gave detailed insights into the mechanisms of terpene biosynthesis by this fungus.

MeSH terms

  • Fusarium / classification
  • Fusarium / metabolism*
  • Gibberellins / metabolism*
  • Magnetic Resonance Spectroscopy
  • Mevalonic Acid / analogs & derivatives*
  • Mevalonic Acid / chemistry
  • Terpenes / isolation & purification
  • Terpenes / metabolism*

Substances

  • Gibberellins
  • Terpenes
  • mevalonolactone
  • Mevalonic Acid