Abstract
Livedoid vasculopathy is a bilateral painful and recurrent cutaneous ulcerative disorder of the legs that leads to atrophie blanche, atrophic white-porcelain scars, and is associated with disorders of fibrinolysis and/or coagulation. We present a young boy with an association between livedoid vasculopathy in the area of a previous involuted cutaneous hemangioma. We found 4 uncommon abnormalities associated with thrombo-occlusive events: heterozygous 20210 A→G genotype of prothrombin, reduced activity of anticoagulation proteins C and S, and elevated lipoprotein (a).
Keywords:
atrophie blanche; hemangioma; livedoid vasculopathy.
MeSH terms
-
Adolescent
-
Aspirin / administration & dosage*
-
Biopsy
-
Blood Coagulation Disorders / complications*
-
Blood Coagulation Disorders / diagnosis
-
Blood Coagulation Disorders / physiopathology
-
Blood Coagulation Tests
-
Diagnosis, Differential
-
Hemangioma / complications*
-
Hemangioma / diagnosis
-
Hemangioma / physiopathology
-
Histological Techniques / methods
-
Humans
-
Leg Ulcer* / etiology
-
Leg Ulcer* / pathology
-
Leg Ulcer* / physiopathology
-
Livedo Reticularis* / diagnosis
-
Livedo Reticularis* / drug therapy
-
Livedo Reticularis* / etiology
-
Livedo Reticularis* / physiopathology
-
Male
-
Pentoxifylline / administration & dosage*
-
Platelet Aggregation Inhibitors / administration & dosage
-
Prothrombin / genetics
-
Skin Neoplasms / complications*
-
Skin Neoplasms / diagnosis
-
Skin Neoplasms / physiopathology
-
Treatment Outcome
-
Ultrasonography, Doppler / methods
Substances
-
Platelet Aggregation Inhibitors
-
Prothrombin
-
Aspirin
-
Pentoxifylline