Abstract
A 70-year-old man who suffered from chronic hepatitis C was infected with HCV genotype 1 and exhibited a high viral load. He had hypertension and had consumed the equivalent of 50 g of ethanol per day. He was treated with pegylated interferon and ribavirin. After 51 weeks, he developed an unsteady gait while walking and demonstrated Barre's sign on the right foot and a headache. Contrast computed tomography showed a subdural hematoma with a mass effect. The patient was treated with drainage and aspiration surgery via a burr hole. Following the drainage procedure, there were no neurological sequelae. Treatment with pegylated interferon and ribavirin was discontinued. Fortunately, a sustained virological response was achieved.
MeSH terms
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Aged
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Antiviral Agents / administration & dosage
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Antiviral Agents / adverse effects*
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Drug Therapy, Combination
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Hematoma, Subdural, Chronic / diagnosis
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Hematoma, Subdural, Chronic / etiology*
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Hematoma, Subdural, Chronic / surgery
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Hepatitis C, Chronic / complications*
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Hepatitis C, Chronic / drug therapy*
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Hepatitis C, Chronic / virology
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Humans
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Interferon alpha-2
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Interferon-alpha / administration & dosage
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Interferon-alpha / adverse effects*
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Male
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Polyethylene Glycols / administration & dosage
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Polyethylene Glycols / adverse effects*
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Recombinant Proteins / administration & dosage
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Recombinant Proteins / adverse effects
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Ribavirin / administration & dosage
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Ribavirin / adverse effects*
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Tomography, X-Ray Computed
Substances
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Antiviral Agents
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Interferon alpha-2
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Interferon-alpha
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Recombinant Proteins
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Polyethylene Glycols
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Ribavirin
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peginterferon alfa-2b