[Infections caused by multi-resistant Gram-positive bacteria (Staphylococcus aureus and Enterococcus spp.)]

Enferm Infecc Microbiol Clin. 2013 Oct;31(8):543-51. doi: 10.1016/j.eimc.2013.08.001. Epub 2013 Sep 14.
[Article in Spanish]

Abstract

Methicillin -resistant Staphylocccus aureus (MRSA) and multirresistant entorococci are still problematic in nosocomial infections and new challenges have emerged for their containment. MRSA has increased the multiresistant profile; it has been described vancomycin and linezolid resistant isolates and isolates with decreased daptomycin susceptibility. Moreover, new clones (ST398) have emerged, initially associated with piggeries, and new mec variants (mecC) with livestock origin that escape to the detection with current molecular methods based on mecA gene have been detected. In enterococci, linzeolid resistant isolates and isolates with deceased susceptibility to daptomycin have been described. Moreover, ampicillin resistant Enterococcus faecium due to β-lactamase production has been recently found in Europe. Control of MRSA isolates and multiresistant enteroccocci should combined antibiotic stewardship strategies and epidemiological measures, including detection of colonized patients in order to reduce colonization pressure and their transmission.

Keywords: Control de infección nosocomial; Enterococcus spp.; Methicillin resistance; Nosocomial infection control; Resistencia a la meticilina; Resistencia a la vancomicina; Staphylococcus aureus; Vancomycin resistance.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Bacterial Typing Techniques
  • Cattle
  • Cattle Diseases / microbiology
  • Clone Cells
  • Cross Infection / drug therapy
  • Cross Infection / epidemiology
  • Cross Infection / microbiology
  • Cross Infection / prevention & control
  • Drug Resistance, Multiple, Bacterial* / genetics
  • Enterococcus / drug effects*
  • Enterococcus / genetics
  • Enterococcus / isolation & purification
  • Global Health
  • Gram-Positive Bacterial Infections / drug therapy
  • Gram-Positive Bacterial Infections / epidemiology
  • Gram-Positive Bacterial Infections / microbiology*
  • Gram-Positive Bacterial Infections / prevention & control
  • Gram-Positive Bacterial Infections / veterinary
  • Humans
  • Methicillin Resistance / genetics
  • Methicillin-Resistant Staphylococcus aureus / classification
  • Methicillin-Resistant Staphylococcus aureus / drug effects*
  • Methicillin-Resistant Staphylococcus aureus / genetics
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification
  • Prevalence
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / prevention & control
  • Staphylococcal Infections / veterinary
  • Swine
  • Swine Diseases / microbiology