The management of atrial fibrillation is complex and is influenced by the type of AF, the severity of symptoms, underlying disease and patient choice. The aim of treatment is to alleviate symptoms, prevent strokes and reduce other complications, such as heart failure. The incidence of AF is increasing due to an ageing population and most health professionals will encounter patients with AF during their career. A widespread knowledge of AF management among the nursing profession is important to ensure that appropriate treatment and patient support are provided. This article is the second in a two-part series on AF. Part one discussed the importance of detecting and treating AF and screening strategies. This second part discusses the management of AF and treatment options, using recent guidelines.