Background and objective: Mediastinal lymphoma or right upper lung cancer is a common cause of superior vena cava obstruction syndrome (SVCOS). Endobronchial ultrasound-guided needle aspiration (EBUS-TBNA) biopsy is applied for the diagnosis of mediastinal mass disease. The aim of this study is to explore the safety and feasibility of EBUS-TBNA biopsy under general anesthesia for the clinical diagnosis of SVCOS.
Methods: Twenty-five cases of SVCOS received EBUS-TBNA under general anesthesia between June 2012 and June 2013. The group consisted of 16 male and 9 female patients aged 33 years to 76 years, with a median age of 62.5.
Results: Twenty-four cases were confirmed to be of malignant pathology, and one case failed to yield a clear pathological diagnosis. No patient experienced any complications related to the operation, such as heavy bleeding and pneumothorax.
Conclusions: For patients presenting with SVCOS, EBUS-TBNA under general anesthesia is a safe and reliable inspection method of high diagnostic yield. This method can be used for routine examination when other means cannot obtain clear pathological diagnosis.
背景与目的 纵隔淋巴瘤或右上肺癌是导致上腔静脉阻塞综合征（superior vena cava obstruction syndrome, SVCOS）的常见病因。气管腔内超声引导针吸活检术（endobronchial ultrasound-guided transbronchial needle aspiration, EBUS-TBNA）在纵隔占位疾病的诊断方面，与外科手术相当。本研究旨在探讨全麻状态下EBUS-TBNA在SVCOS临床病因诊断中的安全性及可行性。 方法 2012年6月-2013年6月25例伴有SVCOS全麻状态下接受EBUS-TBNA的患者，其中男16例，女9例；年龄33岁-76岁，中位62.5岁。 结果 24例病理学证实为恶性肿瘤，确诊率为96.0%（24/25），1例未能获得明确病理诊断；所有患者均未出现与操作相关的并发症，包括大量出血与气胸。结论 对伴有SVCOS的患者，全麻状态下EBUS-TBNA仍是一种确诊率高、安全可靠的微创检查方法，可作为其他手段不能明确病理诊断的常规检查。