Finding a sugary foothold: how antibiotics pave the way for enteric pathogens

Cell Host Microbe. 2013 Sep 11;14(3):225-7. doi: 10.1016/j.chom.2013.08.008.

Abstract

Antibiotic therapy predisposes the host to infections with human enteropathogens. In a recent study, Ng et al. (2013) demonstrate that antibiotic-mediated disruption of the microbial food web gives rise to free microbiota-liberated monosaccharides in the gut, which can promote growth of enteropathogenic bacteria.

Publication types

  • Comment

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology*
  • Carbohydrate Metabolism / drug effects*
  • Clostridioides difficile / physiology*
  • Enterocolitis, Pseudomembranous / microbiology*
  • Female
  • Intestinal Mucosa / microbiology*
  • Male
  • Salmonella Infections / microbiology*
  • Salmonella typhimurium / physiology*

Substances

  • Anti-Bacterial Agents