Mirror mirror on the wall: By taking advantage of the unique structural features of L-DNA, the first examples of left-helical enantioselective induction in the field of DNA-based asymmetric catalysis were realized. Most importantly, this approach is the only one that allows a reliable and predictable access to both enantiomers for any given reaction.
Keywords: Friedel-Crafts reaction; L-DNA; Michael addition; asymmetric catalysis; biohybrid catalyst.
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