Review: comparison of PET rubidium-82 with conventional SPECT myocardial perfusion imaging

Clin Physiol Funct Imaging. 2014 May;34(3):163-70. doi: 10.1111/cpf.12083. Epub 2013 Sep 13.

Abstract

Nuclear cardiology has for many years been focused on gamma camera technology. With ever improving cameras and software applications, this modality has developed into an important assessment tool for ischaemic heart disease. However, the development of new perfusion tracers has been scarce. While cardiac positron emission tomography (PET) so far largely has been limited to centres with on-site cyclotron, recent developments with generator produced perfusion tracers such as rubidium-82, as well as an increasing number of PET scanners installed, may enable a larger patient flow that may supersede that of gamma camera myocardial perfusion imaging.

Keywords: cardiac PET; cardiac SPECT; cardiology; myocardial perfusion imaging; rubidium.

Publication types

  • Review

MeSH terms

  • Coronary Circulation*
  • Heart Diseases / diagnostic imaging*
  • Heart Diseases / physiopathology
  • Humans
  • Myocardial Perfusion Imaging / methods*
  • Positron-Emission Tomography*
  • Predictive Value of Tests
  • Rubidium Radioisotopes*
  • Tomography, Emission-Computed, Single-Photon*

Substances

  • Rubidium Radioisotopes