This article reviews the history of hair follicle regeneration from follicular fragments and dissociated cells. The challenges of trichogenic in vitro culture and subsequent delivery into the patient are discussed, as well as cosmetic acceptance, recent achievements on regeneration of human hair follicles, and new potential cell sources for hair regeneration.
Keywords: Cell therapy; Dermal papilla; Hair follicle; Hair transplantation; Induced pluripotent stem cells (iPS); Regenerative medicine; Trichogenicity.
Copyright © 2013. Published by Elsevier Inc.