Review article: Regenerative techniques for repair of rotator cuff tears

Zafar Ahmad; Fran Henson; John Wardale; Ali Noorani; Graham Tytherleigh-Strong; Neil Rushton

doi:10.1177/230949901302100223

Review article: Regenerative techniques for repair of rotator cuff tears

J Orthop Surg (Hong Kong). 2013 Aug;21(2):226-31. doi: 10.1177/230949901302100223.

Authors

Zafar Ahmad¹, Fran Henson, John Wardale, Ali Noorani, Graham Tytherleigh-Strong, Neil Rushton

Affiliation

¹ Department of Orthopaedics, Norfolk and Norwich University Hospital, Norwich, United Kingdom.

PMID: 24014790
DOI: 10.1177/230949901302100223

Abstract

The failure rate of rotator cuff repair is high. Regenerative techniques using material scaffolds, stem cells, and growth factors help augment repair and regenerate tissue. We reviewed the literature of various regenerative techniques in terms of (1) enhancing the repair process, (2) tissue regeneration, (3) mechanical strength, and (4) clinical outcome.

Keywords: regeneration; rotator cuff; tendon injuries; tissue engineering.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Humans
Intercellular Signaling Peptides and Proteins / pharmacology
Intercellular Signaling Peptides and Proteins / physiology
Platelet-Rich Plasma / physiology
Regeneration*
Rotator Cuff / drug effects
Rotator Cuff / physiology
Rotator Cuff Injuries*
Stem Cell Transplantation
Tendon Injuries / physiopathology*
Tendons / transplantation
Wound Healing / drug effects
Wound Healing / physiology

Substances

Intercellular Signaling Peptides and Proteins