The many layers of specification and plasticity in the neocortex

Neuron. 2013 Sep 4;79(5):829-31. doi: 10.1016/j.neuron.2013.08.021.

Abstract

In this issue of Neuron, Li et al. (2013) show that transgenically eliminating thalamocortical neurotransmission disrupts the formation of barrel columns in the somatosensory cortex and cortical lamination, providing evidence for the importance of extrinsic activity-dependent factors in cortical development.

Publication types

  • Comment

MeSH terms

  • Animals
  • Evoked Potentials, Somatosensory / physiology*
  • Glutamic Acid / physiology*
  • Neural Pathways / physiology*
  • Neurons / physiology*
  • Somatosensory Cortex / growth & development*
  • Synaptic Transmission / physiology*
  • Thalamus / cytology*

Substances

  • Glutamic Acid