MI paste plus and PreviDent fluoride varnish appear no more effective than normal home care for improving the appearance of white spot lesions

J Evid Based Dent Pract. 2013 Sep;13(3):114-6. doi: 10.1016/j.jebdp.2013.07.012.

Abstract

Article title and bibliographic information: Effectiveness of MI Paste Plus and PreviDent fluoride varnish for treatment of white spot lesions: a randomized controlled trial. Huang GJ, Roloff-Chiang B, Mills BE, Shalchi S, Spiekerman C, Korpak AM, Starrett JL, Greenlee GM, Drangsholt RJ, Matunas JC. Am J Orthod Dentofacial Orthop 2013;143:31-41.

Reviewer: Carmen Llena-Puy

Purpose/question: The authors' aim was to compare the effectiveness of MI Paste Plus and PreviDent fluoride varnish (22,600 ppm of fluoride) with a standard oral hygiene regimen with toothpaste (1100 ppm of fluoride; Colgate Oral Pharmaceuticals)--control group--in improving the appearance of white spot lesions (WSLs) after orthodontic treatment during 8 weeks of follow-up

Source of funding: National Institute of Dental and Craniofacial Research

Type of study/design: Randomized controlled trial

Level of evidence: Level 1: Good-quality, patient-oriented evidence

Strength of recommendation grade: Not applicable.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Cariostatic Agents / therapeutic use*
  • Caseins / administration & dosage*
  • Dental Caries / drug therapy*
  • Female
  • Fluorides, Topical / therapeutic use*
  • Fluorine / administration & dosage*
  • Humans
  • Male

Substances

  • Cariostatic Agents
  • Caseins
  • Fluorides, Topical
  • Fluorine