Abstract
Eight-hundred and twenty-five patients attending the hospital with clinical signs and symptoms of collagen diseases were tested for anti-SSA/Ro antibody. The frequency of positivity to SSA/Ro was significantly higher in females, 11.0%, than in males, 3.2% (P less than 0.01). Five babies born to anti-SSA/Ro positive mothers all had neonatal lupus erythematosus and in one there were various cardiac abnormalities.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Antibodies, Antinuclear / analysis*
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Autoantigens / immunology
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Child
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Female
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Humans
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Infant, Newborn
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Lupus Erythematosus, Systemic / immunology*
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Male
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Middle Aged
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Pregnancy
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RNA, Small Cytoplasmic*
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Ribonucleoproteins*
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Risk Factors
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Sex Factors
Substances
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Antibodies, Antinuclear
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Autoantigens
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RNA, Small Cytoplasmic
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RO60 protein, human
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Ribonucleoproteins
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SS-A antibodies
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SS-A antigen
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SS-B antibodies