Polyethylene glycol modification of serpins improves therapeutic potential

Biol Chem Hoppe Seyler. 1990 May:371 Suppl:101-9.

Authors

A E Mast¹, G Salvesen, F H Brucato, H P Schnebli, S V Pizzo

Affiliation

¹ Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710.

PMID: 2400571

No abstract available

MeSH terms

Angiotensin III / pharmacokinetics
Animals
Half-Life
Iodine Radioisotopes
Kinetics
Mice
Oxidation-Reduction
Polyethylene Glycols / pharmacology*
Serpins / chemical synthesis*
Serpins / pharmacokinetics
Serpins / therapeutic use
alpha 1-Antichymotrypsin / pharmacology
alpha 1-Antitrypsin / pharmacology

Substances

Iodine Radioisotopes
Serpins
alpha 1-Antichymotrypsin
alpha 1-Antitrypsin
Angiotensin III
Polyethylene Glycols