Unprecedented ortho-acylation of azoxybenzenes with α-oxocarboxylic acids by Pd-catalyzed C-H activation and decarboxylation

Chem Commun (Camb). 2013 Oct 14;49(80):9170-2. doi: 10.1039/c3cc45492d. Epub 2013 Aug 29.

Abstract

A palladium-catalyzed ortho-acylation reaction of azoxybenzenes with α-oxocarboxylic acids was developed in the presence of K2S2O8. The established methodology provides a direct approach to obtain acylated azoxybenzenes in good yields.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acylation
  • Azo Compounds / chemistry*
  • Carbon / chemistry
  • Catalysis
  • Decarboxylation
  • Hydrogen / chemistry
  • Palladium / chemistry*
  • Stereoisomerism

Substances

  • Azo Compounds
  • Palladium
  • Carbon
  • Hydrogen
  • fenazox