High incidence of Dacron conduit stenosis for extracardiac Fontan procedure

J Thorac Cardiovasc Surg. 2014 May;147(5):1568-72. doi: 10.1016/j.jtcvs.2013.07.013. Epub 2013 Aug 26.

Abstract

Objectives: Extracardiac conduits are widely used to complete a Fontan circulation in patients with univentricular hearts. Although polytetrafluoroethylene conduits have proven good long-term patency, Dacron (polyethylene terephthalate) prostheses are still infrequently applied, with, as yet, no information on the long-term patency.

Methods: All patients who received an extracardiac Dacron conduit (n = 12) were retrospectively studied. The initial conduit size was 16 mm in all recipients. The mean age at Fontan completion was 3.1 ± 0.7 years. Patients with clinical symptoms and/or significant conduit stenosis (>50% of diameter) underwent reoperation.

Results: Of the 12 patients, 8 underwent reoperation (75%) at a mean interval of 6.5 ± 1.8 years after the Fontan operation. All conduits were replaced by an 18-mm polytetrafluoroethylene graft. The explants showed ubiquitous tissue deposits on the inner surface, with a residual internal diameter from 8 to 11 mm. All patients survived the extracardiac conduit replacement. Recovery was uneventful, except that 1 patient experienced long-lasting pleural fluid drainage. The mean hospital stay was 10.6 ± 12.0 days.

Conclusions: The incidence of extracardiac Dacron conduit stenosis in total cavopulmonary connection patients is high. These data indicate that the use of this type of conduit should be avoided. Vigilant follow-up is advised for those patients who have undergone Fontan completion with a Dacron extracardiac conduit.

MeSH terms

  • Blood Vessel Prosthesis Implantation / adverse effects*
  • Blood Vessel Prosthesis Implantation / instrumentation*
  • Blood Vessel Prosthesis*
  • Child, Preschool
  • Constriction, Pathologic
  • Device Removal
  • Fontan Procedure / adverse effects*
  • Graft Occlusion, Vascular / diagnosis
  • Graft Occlusion, Vascular / epidemiology*
  • Graft Occlusion, Vascular / surgery
  • Heart Defects, Congenital / physiopathology
  • Heart Defects, Congenital / surgery*
  • Humans
  • Incidence
  • Length of Stay
  • Netherlands / epidemiology
  • Polyethylene Terephthalates*
  • Prosthesis Design
  • Reoperation
  • Retrospective Studies
  • Time Factors
  • Treatment Outcome

Substances

  • Polyethylene Terephthalates