Outbreak of extensively drug-resistant Acinetobacter baumannii indigo-pigmented strains

J Clin Microbiol. 2013 Nov;51(11):3726-30. doi: 10.1128/JCM.01388-13. Epub 2013 Aug 28.

Abstract

Acinetobacter baumannii pigmented strains are not common in clinical settings. Here, we report an outbreak caused by indigo-pigmented A. baumannii strains isolated in an acute care hospital in Argentina from March to September 2012. Pan-PCR assays exposed a unique pattern belonging to the recently described regional CC113(B)/CC79(P) clonal complex that confirms the relevant relationships among the indigo-pigmented A. baumannii strains. All of them were extensively drug resistant and harbored different genetic elements associated with horizontal genetic transfer, such as the transposon Tn2006, class 2 integrons, AbaR-type islands, IS125, IS26, strA, strB, florR, and the small recombinase ISCR2 associated with the sul2 gene preceded by ISAba1.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter Infections / epidemiology*
  • Acinetobacter Infections / microbiology*
  • Acinetobacter baumannii / drug effects*
  • Acinetobacter baumannii / isolation & purification
  • Acinetobacter baumannii / metabolism*
  • Adult
  • Aged
  • Aged, 80 and over
  • Animals
  • Argentina
  • Cluster Analysis
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • Disease Outbreaks*
  • Drug Resistance, Multiple, Bacterial*
  • Female
  • Genotype
  • Humans
  • Interspersed Repetitive Sequences
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Molecular Typing
  • Pigments, Biological / metabolism*
  • Polymerase Chain Reaction
  • Sequence Analysis, DNA

Substances

  • DNA, Bacterial
  • Pigments, Biological

Associated data

  • GENBANK/KF410895
  • GENBANK/KF410896