[Relationship between UGT1A and irinotecan-related toxicity]

Zhonghua Zhong Liu Za Zhi. 2013 Apr;35(4):241-3. doi: 10.3760/cma.j.issn.0253-3766.2013.04.001.
[Article in Chinese]
No abstract available

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents, Phytogenic / adverse effects
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Camptothecin / adverse effects
  • Camptothecin / analogs & derivatives*
  • Camptothecin / therapeutic use
  • Colorectal Neoplasms* / drug therapy
  • Colorectal Neoplasms* / genetics
  • Diarrhea / chemically induced
  • Glucuronosyltransferase / genetics*
  • Humans
  • Irinotecan
  • Neutropenia / chemically induced*
  • Polymorphism, Single Nucleotide*

Substances

  • Antineoplastic Agents, Phytogenic
  • Irinotecan
  • UGT1A1 enzyme
  • Glucuronosyltransferase
  • Camptothecin