Fluorescence imaging enabled biodegradable photostable polymeric micelles

Adv Healthc Mater. 2014 Feb;3(2):182-6. doi: 10.1002/adhm.201300145. Epub 2013 Aug 26.

Abstract

Amphiphilic biodegradable photoluminescent polymers (ABPLPs) composed of a biodegradable fluorescent polymer and methoxy poly (ethyleneglycol) demonstrate intrinsic bright, tunable, and stable fluorescence emission. ABPLP micelles elicit minor cellular toxicity and can be used for cell and tissue imaging both in vitro and in vivo.

Keywords: biodegradable; drug delivery; fluorescence imaging; fluorescent polymer; micelle.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Diagnostic Imaging / methods*
  • Drug Delivery Systems
  • Fluorescence*
  • Micelles
  • Polymers / chemistry*

Substances

  • Micelles
  • Polymers