Abstract
Mesoporous silica nanoparticles (MSNs) have been surface-functionalized with choline moieties encircled by sulfonatocalix[4]arenes. Two enzyme cleavable sites are incorporated in the stalks for specific enzymes to regulate the release of loaded cargos from MSNs. These gated materials show a clear enzymatic response and proven orthogonality.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Biocompatible Materials / chemistry
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Biocompatible Materials / metabolism
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Calixarenes / chemistry*
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Choline / chemistry
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Enzymes / metabolism*
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Esterases / metabolism
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Hydrogen-Ion Concentration
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Nanoparticles / chemistry*
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Phenols / chemistry*
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Porosity
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Rhodamines / chemistry
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Rotaxanes / chemistry*
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Silicon Dioxide / chemistry*
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Sulfonic Acids / chemistry
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Surface Properties
Substances
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Biocompatible Materials
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Enzymes
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MCM-41
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Phenols
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Rhodamines
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Rotaxanes
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Sulfonic Acids
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calix(4)arene
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Calixarenes
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Silicon Dioxide
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Esterases
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rhodamine B
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Choline