Understand that in addition to the problems inherent to mental conditions the people suffer associated medical conditions that further complicate their condition and endanger its vitality is paramount. Of course this requires fundamental premise construct understanding of mental health within the medical model of care. As mentioned above we make the following literature review focusing on understanding the interaction between depression and cardiovascular disease mainly and reviewing other comorbidities and their impact on our patients. We show also that several factors contribute to poor physical health of people with psychiatric disorders including different individual choices in lifestyle determined by its pathologies and on the other hand a marked disparity in access, utilization and health care provision.