Pomalidomide

Blood. 2013 Oct 3;122(14):2305-9. doi: 10.1182/blood-2013-05-484782. Epub 2013 Aug 23.

Abstract

This spotlight review focuses on the second-generation immunomodulatory drug pomalidomide, which was recently approved by the US Food and Drug Administration. This drug was approved for patients with multiple myeloma who have received at least 2 prior therapies, including lenalidomide and bortezomib, and have demonstrated disease progression on or within 60 days of completion of the last therapy. This review focuses on the clinical trial data that led to approval and provides advice for treating physicians who are now prescribing this drug for patients.

Publication types

  • Review

MeSH terms

  • Clinical Trials as Topic*
  • Humans
  • Immunologic Factors / therapeutic use*
  • Immunomodulation
  • Multiple Myeloma / drug therapy*
  • Thalidomide / analogs & derivatives*
  • Thalidomide / therapeutic use

Substances

  • Immunologic Factors
  • Thalidomide
  • pomalidomide