Effective implementation of time-frequency matched filter with adapted pre and postprocessing for data-dependent detection of newborn seizures

Abstract

Neonatal EEG seizures often manifest as nonstationary and multicomponent signals, necessitating analysis in the time-frequency (TF) domain. This paper presents a novel neonatal seizure detector based on effective implementation of the TF matched filter. In the detection process, the TF signatures of EEG seizure are extracted to construct the TF templates used by the matched filter. Matching pursuit (MP) decomposition and narrowband filtering are proposed for the reduction of artifacts prior to seizure detection. Geometrical correlation is used to consolidate the multichannel detections and to reduce the number of false detections due to remnant artifacts. A data-dependent threshold is defined for the classification of EEG. Using 30 newborn EEG records with seizures, the classification process yielded an overall detection accuracy of 92.4% with good detection rate (GDR) of 84.8% and false detection rate of 0.36FD/h. Better detection performance (accuracy >95%) was recorded for relatively long EEG records with short seizure events.

Keywords: EEG; Matched filter; Neonatal seizure detection; Time–frequency analysis; Time–frequency distribution.