Invasive trichosporonosis in an AIDS patient: case report and review of the literature

Int J STD AIDS. 2014 Jan;25(1):70-5. doi: 10.1177/0956462413487716. Epub 2013 Jul 29.

Abstract

Invasive Trichosporon infection is a rare, life-threatening infection in immunocompromised patients. It has been reported as an emerging opportunistic infection in those with acquired immune deficiency syndrome (AIDS). Only 12 cases of invasive trichosporonosis in patients with HIV have been documented, none in Southeast Asia. We report a case of fatal, disseminated trichosporonosis in a Filipino AIDS patient with severe cutaneous and pulmonary involvement. Invasive trichosporonosis should be considered in HIV-positive patients with disseminated fungal infection since this may be refractory to conventional antifungal treatment.

Keywords: HIV; Philippines; T. asahii; Trichosporon; acquired immunodeficiency syndrome; case reports [publication type]; cryptococcosis; mycoses; opportunistic infections; review [publication type].

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use
  • Dermatomycoses / complications*
  • Dermatomycoses / microbiology
  • Dermatomycoses / pathology
  • Fatal Outcome
  • Humans
  • Immunocompromised Host
  • Male
  • Opportunistic Infections / complications*
  • Opportunistic Infections / microbiology
  • Opportunistic Infections / pathology
  • Trichosporon / isolation & purification*
  • Trichosporonosis / diagnosis*

Substances

  • Antifungal Agents