Real-time 3-dimensional contrast-enhanced ultrasound in detecting hemorrhage of blunt renal trauma

Am J Emerg Med. 2013 Oct;31(10):1427-31. doi: 10.1016/j.ajem.2013.06.013. Epub 2013 Aug 19.

Abstract

Objectives: The objective of this study is to evaluate the diagnostic value of real-time 3-dimensional contrast-enhanced ultrasound in the hemorrhage of blunt renal trauma.

Methods: Eighteen healthy New Zealand white rabbits were randomly divided into 3 groups. Blunt renal trauma was performed on each group by using minitype striker. Ultrasonography, color Doppler flow imaging, and contrast-enhanced 2-dimensional and real-time 3-dimensional ultrasound were applied before and after the strike. The time to shock and blood pressure were subjected to statistical analysis. Then, a comparative study of ultrasound and pathology was carried out.

Results: All the struck kidneys were traumatic. In the ultrasonography, free fluid was found under the renal capsule. In the color Doppler flow imaging, active hemorrhage was not identified. In 2-dimensional contrast-enhanced ultrasound, active hemorrhage of the damaged kidney was characterized. Real-time 3-dimensional contrast-enhanced ultrasound showed a real-time and stereoscopic ongoing bleeding of the injured kidney. The wider the hemorrhage area in 4-dimensional contrast-enhanced ultrasound was, the faster the blood pressure decreased.

Conclusions: Real-time 3-dimensional contrast-enhanced ultrasound is a promising noninvasive tool for stereoscopically and vividly detecting ongoing hemorrhage of blunt renal trauma in real time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Contrast Media
  • Disease Models, Animal
  • Female
  • Hemorrhage / diagnostic imaging*
  • Hemorrhage / etiology
  • Imaging, Three-Dimensional / methods
  • Kidney / diagnostic imaging
  • Kidney / injuries*
  • Kidney Diseases / diagnostic imaging*
  • Kidney Diseases / etiology
  • Male
  • Phospholipids
  • Rabbits
  • Sulfur Hexafluoride
  • Ultrasonography
  • Wounds, Nonpenetrating / complications
  • Wounds, Nonpenetrating / diagnostic imaging*

Substances

  • Contrast Media
  • Phospholipids
  • contrast agent BR1
  • Sulfur Hexafluoride